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San Francisco 49ers take on Bronkes.

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49ers vs. The Bronkes i.e. Russell Wilson and Garoppolo will once again come face to face.

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The San Francisco 49ers will try again on September 25 for a second straight win against the Broncos.

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The Denver Broncos will visit Empower Field in Mile High in its Week 3 edition.

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The Denver Broncos and 49ers will face off on September 25 in the evening.

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This game will be telecasted on national-level TV.

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The 49ers will be led this season by Jimmy Garoppolo.

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Jimmy Garoppolo led his team to victory in the first match.